Key result
Baseline C-reactive protein was significantly higher in women than men (3.0 vs 2.1 mg/L; P<0.001) and independently predicted cardiovascular risk (P=0.033), though event rates were similar by sex.
Why the study?
Does baseline C-reactive protein level differ between men and women with chronic stable angina, and does it predict cardiovascular risk?
Population
911 consecutive patients (327 women) with typical exertional angina (chronic stable angina)
Design
Cohort
Follow-up
1.0 to 3.7 years
Authors
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CRP elevation predicts risk similarly despite higher levels in women; extends observational data but should not yet change sex-specific management.
Cohort (n=911)
Does baseline C-reactive protein level differ between men and women with chronic stable angina, and does it predict cardiovascular risk?
p-value: p=0.033
In patients with chronic stable angina, baseline C-reactive protein levels are higher in women than men and in women on hormone replacement therapy, but elevated CRP remains an independent predictor of cardiovascular risk across the entire cohort.
Xavier García–Moll (2000) conducted a cohort in chronic stable angina (n=911). C-reactive protein was evaluated on cardiovascular risk (p=0.033). Baseline C-reactive protein was significantly higher in women than men (3.0 vs 2.1 mg/L; P<0.001) and independently predicted cardiovascular risk (P=0.033), though event rates were similar by sex.
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