We conducted an electron microscopic study on the alterations in the temporomandibular joint (TMJ) synovium of the monkey after it was subjected to unilateral bite-raising, by means of a maxillary occlusal splint. The uptake of intravenously injected horseradish peroxidase (HRP) by type A cells was demonstrated in the disturbed TMJ. The uptake of HRP decreased three to six wk after occlusal alteration, and was the same as in normal type A synovial cells after 16 wk.
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Y. Kubo (1987) studied this question.
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