Key result
Low high-density lipoprotein is an independent risk factor for myocardial infarction.
Key points are not available for this paper at this time.
Design
Review
Continue HDL assessment in MI risk stratification; leaves open whether raising levels improves outcomes.
Low HDL is an independent risk factor for myocardial infarction. This paper reviews our current understanding of HDL, HDL structure and function, HDL subclasses, the relationship of low HDL with myocardial infarction, HDL targeted therapy, and clinical trials and studies. Furthermore potential new agents, such as alirocumab (praluent) and evolocumab (repatha) are discussed.
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Ramı́rez et al. (2015) studied this question. Low high-density lipoprotein is an independent risk factor for myocardial infarction.
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