History of the Wastewater Assessment of Polio and Non-Polio Enteroviruses in the Slovak Republic in 1963–2019

Figures

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  Figure 1. (a) Generalized additive models (GAM) showing temporal trends in the probability of enteroviruses (EV) strains, coxsackievirus A (CVA), CVB, echoviruses (E), and polioviruses (PV) occurrence during the first period (1963–1998). (b) Temporal trends in the probability of EV groups occurrence during the second period (1999–2019). GAM-based estimates (lines) are displayed along with their 95% confidence intervals.

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  Figure 2. Temporal trends in the probability of enterovirus (EV) strains, coxsackievirus A (CVA), CVB, echoviruses (E) and polioviruses (PV) occurrence during the second period (1999–2019). Generalized additive models (GAM)-based estimates (lines) are displayed along with their 95% confidence intervals.

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  Figure 3. Canonical correspondence analysis (CCA) ordination plot showing temporal changes in the assemblage composition of enterovirus (EV) strains, coxsackievirus A (CVA), CVB, echoviruses (E), polioviruses (PV), and vaccine-derived poliovirus (VDPV) during the second period (1999–2019). Only the most frequent strains with the best fit to the long-term temporal trend (first axis) are displayed (in italics). Sample scores are labelled by years (in blue), and the strain scores, representing the maxima of relative abundances, are shown in red. The ordination plot is scaled symmetrically; variation explained by the ordination axes is displayed in parentheses.