Uncertainty Analysis in the Estimation of Exposure

This article addresses the ubiquitous nature of uncertainty in industrial hygiene-related risk assessment and defines two basic types of uncertainty: natural variability and a basic lack of knowledge. A relatively simple physical-chemical modeling example is provided as an illustration in which uncertainty and sensitivity are described using two methods, a conventional technique and a readily available and user-friendly computer simulation software. The need for and value of monitoring data for validation and as a “reality check” is emphasized.