Key result
A review of non-invasive imaging modalities for measuring left ventricular ejection fraction highlights common sources of measurement error and the importance of recognizing and preventing them.
Accurate measurement of LVEF requires understanding and recognizing the potential sources of error inherent to various non-invasive imaging modalities.
Recognizing modality-specific errors is essential for reliable LVEF assessment; leaves open standardization of measurement protocols.
Prognosis and therapeutic decisions are often based on left ventricular ejection fraction (LVEF), which means the LVEF needs to be accurately measured. Many imaging modalities can measure LVEF. Each of these modalities is subject to measurement errors that can lead to the inaccurate calculation of LVEF. This article reviews the most common non-invasive imaging modalities – i.e., echocardiography, magnetic resonance imaging (MRI), computed tomography (CT), radionuclide angiography, gated myocardial perfusion single-photon emission computed tomography (SPECT) and gated myocardial perfusion positron emission tomography (PET) – used to measure LVEF, as well as the common sources of error with each of them. It is important to understand these sources of errors in order to prevent them, and recognise them when they do occur so that they can be corrected if possible.
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Foley et al. (2012) conducted a review in Left ventricular ejection fraction measurement. Non-invasive imaging modalities (echocardiography, MRI, CT, radionuclide angiography, SPECT, PET) was evaluated. A review of non-invasive imaging modalities for measuring left ventricular ejection fraction highlights common sources of measurement error and the importance of recognizing and preventing them.
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