Key result
The Detect-Plus combination test demonstrated 100% sensitivity with only 0.56% presumed false-positives for detecting HIV and HTLV antibodies compared to routine screening assays.
Why the study?
Does the Detect-Plus combination test accurately detect antibodies to HIV-1, HIV-2, HTLV-I, and HTLV-II compared to routine commercial screening assays in STD patients?
Population
356 sexually transmitted disease (STD) patients
Comparison
Detect-Plus combination test vs Three routine commercial screening assays and…
Design
Cross-sectional
Authors
Loading...
Supports combined retroviral screening evaluation in STD clinics; leaves open prospective performance and practice impact.
Cross-Sectional (n=356)
Does the Detect-Plus combination test accurately detect antibodies to HIV-1, HIV-2, HTLV-I, and HTLV-II compared to routine commercial screening assays in STD patients?
The Detect-Plus combination assay is a highly sensitive and specific screening method for simultaneous detection of antibodies to human retroviruses.
Zhang et al. (1992) conducted a cross-sectional in Sexually transmitted disease (STD) (n=356). Detect-Plus combination test vs. Routine commercial screening assays was evaluated on Sensitivity and specificity for detection of antibodies to HIV-1, HIV-2, HTLV-I, and HTLV-II. The Detect-Plus combination test demonstrated 100% sensitivity with only 0.56% presumed false-positives for detecting HIV and HTLV antibodies compared to routine screening assays.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: