Key result
Among 152 hypertensive patients, 36.8% had uncontrolled blood pressure, and hypervolemia was significantly associated with poor blood pressure control (p=0.003).
Why the study?
Despite adequate medical therapy, over half of hypertensive patients have blood pressures persistently above the treatment threshold, prompting investigation into factors responsible for uncontrolled hypertension.
Cross-Sectional (n=152)
No
Effect estimate: r=0.67
p-value: p=0.003
In a Pakistani tertiary care cohort, over a third of hypertensive patients had uncontrolled blood pressure, with hypervolemia identified as a significant contributing factor.
Hypervolemia may contribute to uncontrolled hypertension; hypothesis-generating for volume-targeted strategies pending prospective data.
Hypertension is a major cause of morbidity and mortality worldwide. In spite of the availability of adequate medical therapy, more than half of the patients have blood pressures persistently above the treatment threshold (140/90 mmHg). Objective: To investigate the factors responsible for uncontrolled hypertension. Materials and Methods: It was a descriptive cross-sectional study. The study population comprised of 152 consecutive hypertensive patients more than 18 years of age presenting to the Nephrology Clinic at Fatima Memorial Hospital during the period of one month (July 2020) were included in this study. The criteria for control was defined as an office BP of less than 140/90 mmHg. Results: 96 patients (63.2%) had controlled blood pressure and 56 patients (36.8%) had uncontrolled blood pressure. Males exhibited uncontrolled BP (59%) more than females. Out of all the factors studied, volume status had a significant effect on control of HTN (p=0.003). Conclusion Control of hypertension in our population is still far being perfect. There is a need to fortify our efforts to control hypertension so as to reduce associated morbidity and mortality. At the same time there is a need to conduct large studies to fully elucidate the factors contributing to uncontrolled hypertension in our population.
No takes yet. Share an insight, caveat, or question.
Sabir et al. (2021) conducted a cross-sectional in Hypertension (n=152). Hypervolemia vs. Euvolemia or hypovolemia was evaluated on Uncontrolled hypertension (BP ≥ 140/90 mmHg) (r=0.67, p=0.003). Among 152 hypertensive patients, 36.8% had uncontrolled blood pressure, and hypervolemia was significantly associated with poor blood pressure control (p=0.003).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: