Key result
Patients undergoing ascending aortic replacement for Stanford type A aortic dissection had a significantly higher early mortality rate (21.2% vs 1.9%) compared to those with ascending aortic aneurysm.
Why the study?
Ascending aortic replacement is challenging, and outcomes, mortality, and morbidity depend on the underlying ascending aortic pathology and the type of operation.
Does ascending aortic replacement for Stanford type A aortic dissection have worse early and short-term outcomes compared to surgery for ascending aortic aneurysm?
Cohort (n=85)
No
Does ascending aortic replacement for Stanford type A aortic dissection have worse early and short-term outcomes compared to surgery for ascending aortic aneurysm?
Absolute Event Rate: 21.2% vs 1.9%
p-value: p=0.003
Ascending aortic replacement for Stanford type A aortic dissection is associated with significantly higher early mortality and lower 1-year survival compared to surgery for ascending aortic aneurysm.
Heightens perioperative caution in type A dissection repair; leaves open whether refined techniques narrow outcome gaps with aneurysm surgery.
Ascending aortic replacement is a challenging and complex surgery. The mortality, morbidity, and outcomes depend on the causes of the ascending aortic pathology and the type of operation. The research was conducted in a single-center, prospective, observational cohort study of patients undergoing ascending aortic replacement due to dissection or aneurysm. In the hospital, mortality, morbidity, and short-term outcomes were measured. A total of 85 patients were included in this study. Of them, 65.9% were male, and 34.1% were female. Thirty-three patients had Stanford type A aortic dissection (STAAD), whereas 52 had ascending aortic aneurysm (ASAA). Early mortality was (21.21% and 1.9%) for STAAD and ASAA, respectively, while the survival rate after one year was (75.8% and 96.15 %) for ascending dissection and aneurysm, respectively. The results of our study show higher early surgical mortality and morbidity and a lower short-term survival rate for STAAD surgery compared with ASAA surgery.
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Anwar et al. (2022) conducted a cohort in Stanford type A aortic dissection and ascending aortic aneurysm (n=85). Stanford type A aortic dissection (STAAD) vs. Ascending aortic aneurysm (ASAA) was evaluated on Early mortality (in-hospital or within 30 days) (p=0.003). Patients undergoing ascending aortic replacement for Stanford type A aortic dissection had a significantly higher early mortality rate (21.2% vs 1.9%) compared to those with ascending aortic aneurysm.
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