Key result
Aortic arch and concomitant root replacement was associated with higher adjusted in-hospital mortality compared to isolated ascending aortic replacement (27.7% vs 16.4%).
Why the study?
Acute Stanford type A aortic dissection is a severe emergency with high mortality, and the extent of surgical repair may impact patient outcomes.
Does extensive surgical repair compared to isolated ascending aortic replacement improve mortality and complications in patients with acute type A aortic dissection?
Population
3702 patients operated for acute type A aortic dissection
Comparison
Different extents of surgical repair vs isolated ascending aortic replacement
Design
Multicentre registry study
Follow-up
10 years
Authors
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Higher mortality with extensive repair supports limiting extent when feasible; leaves open confirmation in randomized trials.
Cohort (n=3,702)
Yes
Does extensive surgical repair compared to isolated ascending aortic replacement improve mortality and complications in patients with acute type A aortic dissection?
Absolute Event Rate: 27.7% vs 16.4%
Limiting the extent of aortic replacement for acute type A aortic dissection, when feasible, may be beneficial in reducing short- and long-term mortality and major complications.
Biancari et al. (2025) conducted a cohort in Acute Stanford type A aortic dissection (n=3,702). Aortic arch and concomitant aortic root replacement vs. Isolated ascending aortic replacement was evaluated on Mortality rate, both in-hospital and at 10 years. Aortic arch and concomitant root replacement was associated with higher adjusted in-hospital mortality compared to isolated ascending aortic replacement (27.7% vs 16.4%).