What question did this study set out to answer?

To evaluate the health effects of influenza and determine the clinical benefits of influenza vaccination in elderly individuals diagnosed with chronic lung disease.

March 2, 1999Annals of Internal Medicine

Relation between Influenza Vaccination and Outpatient Visits, Hospitalization, and Mortality in Elderly Persons with Chronic Lung Disease

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Authors

KNKristin L. NicholUniversity of Minnesota

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Implication

Retrospective cohort study shows lower hospitalizations and mortality following influenza vaccination in elderly persons with chronic lung disease, indicating substantial clinical benefits.

Key Points

To evaluate the health effects of influenza and determine the clinical benefits of influenza vaccination in elderly individuals diagnosed with chronic lung disease.
Retrospective, multiseason cohort study analyzing administrative databases from a large managed care organization.
Evaluated all elderly members with a prior diagnosis of chronic lung disease across the 1993–1994, 1994–1995, and 1995–1996 influenza seasons.
Compared outpatient visits, hospitalizations, and mortality between vaccinated and unvaccinated cohorts after adjusting for baseline demographic and health characteristics.
Vaccination rates exceeded 70% each season, while unvaccinated individuals experienced twice the rate of pneumonia and influenza hospitalizations during influenza seasons compared with interim periods.
Influenza vaccination was associated with fewer hospitalizations for pneumonia and influenza (adjusted risk ratio, 0.48 [95% CI, 0.28 to 0.82]).
Vaccination was associated with a reduced risk of death (adjusted odds ratio, 0.30 [95% CI, 0.21 to 0.43]) and fewer outpatient visits for pneumonia, influenza, and all respiratory conditions.

Cite This Study

Kristin L. Nichol (1999) studied this question.

synapsesocial.com/papers/6a92c115eba2c67b4da5ff4a https://doi.org/10.7326/0003-4819-130-5-199903020-00003

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Implication

Retrospective cohort study shows lower hospitalizations and mortality following influenza vaccination in elderly persons with chronic lung disease, indicating substantial clinical benefits.

Relation between Influenza Vaccination and Outpatient Visits, Hospitalization, and Mortality in Elderly Persons with Chronic Lung Disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Relation between Influenza Vaccination and Outpatient Visits, Hospitalization, and Mortality in Elderly Persons with Chronic Lung Disease

Discussion

Member takes

Implication

Key Points

Cite This Study

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