Highlights the importance of considering angiosarcoma in the differential diagnosis of skin changes resembling late radiation dermatitis after breast irradiation.
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May prompt consideration of angiosarcoma in post-radiation skin changes; leaves open need for prospective validation.
Angiosarcoma arising in the breast is a very rare malignancy. Of the small number of reported cases, most arose in the breast after breast irradiation. A case is reported of angiosarcoma arising in the breast more than 7 years after lumpectomy and breast irradiation for carcinoma of the breast. The initial appearance was very similar to the changes of late radiation dermatitis and the true nature of the malignant lesion was not known for 23 months.
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Deutsch et al. (1998) studied this question.
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