Key result
Troponin level elevation (≥0.04 ng/mL) in patients hospitalized for HFpEF decompensation was an independent predictor of higher mortality compared to normal troponin levels (P=0.005).
Why the study?
Does troponin level elevation predict mortality in patients hospitalized for HFpEF decompensation?
Population
363 consecutive patients admitted for heart failure with preserved ejection fraction decompensation that was…
Comparison
Troponin level elevation vs Normal troponin level
Design
Cohort
Authors
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Supports troponin elevation as prognostic marker in decompensated HFpEF; hypothesis-generating and should not yet change practice.
Cohort (n=363)
Does troponin level elevation predict mortality in patients hospitalized for HFpEF decompensation?
p-value: p=0.005
Elevated troponin I levels (≥0.04 ng/mL) serve as an independent prognostic marker for increased mortality in patients hospitalized with decompensated HFpEF.
Thawabi et al. (2017) conducted a cohort in Decompensated heart failure with preserved ejection fraction (HFpEF) (n=363). Troponin level elevation (troponin I ≥0.04 ng/mL) vs. Normal troponin level was evaluated on Short-, intermediate-, and long-term all-cause mortality (p=0.005). Troponin level elevation (≥0.04 ng/mL) in patients hospitalized for HFpEF decompensation was an independent predictor of higher mortality compared to normal troponin levels (P=0.005).
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