Key result
Xin repeats define a novel, repetitive actin-binding motif present in muscle proteins (Xin and XIRP2) that bind to and stabilize the actin-based cytoskeleton.
Population
Cultured cells and skeletal muscle actin (in vitro models)
Design
Preclinical
Authors
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May guide cytoskeletal research in muscle; extends actin-binding protein family but leaves open human disease relevance.
Xin repeats define a novel actin-binding motif present in at least two different muscle proteins, establishing a new family of actin-binding proteins.
Pacholsky et al. (2004) studied this question. Xin repeats was evaluated on Actin-binding and stabilization of actin-based cytoskeleton. Xin repeats define a novel, repetitive actin-binding motif present in muscle proteins (Xin and XIRP2) that bind to and stabilize the actin-based cytoskeleton.
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