July 10, 2009European Journal of Neurology
In‐hospital myocardial infarction following acute ischaemic stroke: an observational study
Key result
In-hospital myocardial infarction following acute ischaemic stroke was associated with increased odds of death or severe dependence at discharge (OR 2.51; 95% CI 1.75-3.59).
Why the study?
Does in-hospital myocardial infarction worsen clinical outcomes (death or severe dependence) in patients with acute ischaemic stroke?
Population
9,180 consecutive patients with acute ischaemic stroke from the Registry of the Canadian Stroke Network…
Comparison
In-hospital myocardial infarction (exposure) vs No in-hospital myocardial infarction
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
May warrant heightened cardiac monitoring after stroke; leaves open whether prevention reduces dependence or mortality.
Study Design
Type
Observational (n=9,180)
Multicenter
Yes
Structured PICO
Does in-hospital myocardial infarction worsen clinical outcomes (death or severe dependence) in patients with acute ischaemic stroke?
P
Population
9,180 consecutive patients with acute ischaemic stroke from a national registry, followed for up to 1 year.
E
Exposure
In-hospital myocardial infarction (exposure)
C
Comparator
No in-hospital myocardial infarction
O
Outcome
Death or severe dependence at hospital discharge and 1 year mortalityhard clinical
Main Result
Odds Ratio: 2.51 (95% CI 1.75–3.59)
Absolute Event Rate: 64.9% vs 35.8%
In-hospital myocardial infarction is a significant medical complication following acute ischaemic stroke, independently associated with increased risk of death or severe dependence at discharge and 1-year mortality.
Cite This Study
Liao et al. (2009) conducted an observational in acute ischaemic stroke (n=9,180). In-hospital myocardial infarction vs. Entire cohort was evaluated on Death or severe dependence at hospital discharge (OR 2.51, 95% CI 1.75-3.59). In-hospital myocardial infarction following acute ischaemic stroke was associated with increased odds of death or severe dependence at discharge (OR 2.51; 95% CI 1.75-3.59).