Key result
Transdermal nitroglycerin significantly increased total exercise duration at 2 hours compared to placebo (14.0 vs 12.5 minutes; p<0.05), with effects maintained at 26 hours.
Why the study?
Does transdermal nitroglycerin improve exercise capacity in patients with stable angina?
RCT (n=20)
Double-blind
Randomized
Does transdermal nitroglycerin improve exercise capacity in patients with stable angina?
Absolute Event Rate: 14% vs 12.5%
p-value: p=<0.05
Transdermal nitroglycerin significantly increases exercise capacity and time to anginal threshold over a 24-hour period in patients with stable angina.
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Supports transdermal nitroglycerin in stable angina; confirms sustained 24-hour exercise benefit in this RCT.
Richard J. Thompson (1986) conducted an RCT in Stable angina (n=20). Transdermal nitroglycerin vs. Placebo was evaluated on Total exercise duration at 2 hours (p=<0.05). Transdermal nitroglycerin significantly increased total exercise duration at 2 hours compared to placebo (14.0 vs 12.5 minutes; p<0.05), with effects maintained at 26 hours.
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