Key result
Desmopressin showed a favorable effect in preventing bleeding during surgery or dental extraction in type II B vWD patients without significant side-effects, even with severe thrombocytopenia (70%).
Why the study?
Does desmopressin safely prevent bleeding in patients with type II B von Willebrand disease?
Does desmopressin safely prevent bleeding in patients with type II B von Willebrand disease?
Desmopressin appears safe and effective for preventing bleeding during minor procedures in selected patients with type II B von Willebrand disease, despite causing transient thrombocytopenia.
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May support desmopressin for minor procedures in selected type IIB vWD; leaves open need for prospective confirmation.
Castaman et al. (1996) conducted a review in Type II B von Willebrand disease. Desmopressin was evaluated on Biological and clinical effects (side-effects and prevention of bleeding). Desmopressin showed a favorable effect in preventing bleeding during surgery or dental extraction in type II B vWD patients without significant side-effects, even with severe thrombocytopenia (70%).
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