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August 1, 1985BloodOpen Access

Type IIB Tampa: a variant of von Willebrand disease with chronic thrombocytopenia, circulating platelet aggregates, and spontaneous platelet aggregation

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Population

4 family members with a new variant of type IIB von Willebrand disease

Design

Case_series

Authors

HSHI SabaMoffitt Cancer CenterSSSR SabaUniversity of South FloridaJDJudith DentMedical University of South Carolina

Discussion

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Implication

Alerts clinicians to atypical type IIB vWD phenotypes; leaves open prevalence and management questions pending additional cases.

Structured PICO

P
Population
4 family members with a new variant of type IIB von Willebrand disease

Identifies a novel variant of type IIB von Willebrand disease presenting with chronic thrombocytopenia and spontaneous platelet aggregation but only moderate bleeding.

Cite This Study

Saba et al. (1985) studied this question.

synapsesocial.com/papers/6a6fac94a528af2d65c31bc4https://doi.org/10.1182/blood.v66.2.282.282
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heightened Interaction between Platelets and Factor VIII/von Willebrand Factor in a New Subtype of von Willebrand's Disease1980 · 374 citations
  2. 2Platelet-type von Willebrand's disease: characterization of a new bleeding disorder1982 · 202 citations
  3. 3Familial Association of Thrombopathia and Antihemophilic Factor (AHF, Factor VIII) Deficiency1972 · 21 citations
  4. 4Preparation of Suspensions of Washed Platelets from Humans1972 · 841 citations
  5. 5Pseudo-von Willebrand's Disease1982 · 228 citations