Moniliasis in Acute Leukaemia

The prolonged use of antibiotics, cortisone, or a combination of both has resulted in an increase in infections with monilia. With the recent advances in the treatment of acute leukaemia to include anti-metabolites, corticoids, and antibiotics, an increased incidence of monilial infections might be expected. This paper reports the clinical and necropsy findings in five cases of acute leukaemia with moniliasis which have occurred at this hospital during the past two years. Four of these were treated with 6-mercaptopurine (6-M.P.), corticoids, and antibiotics. The fifth was untreated in hospital, but probably received antibiotics for some time before admission.