Answers are grounded in this paper and cite their sources.
The mouse mammary tumor virus (MMTV) superantigen induces T-cell production of cytokines, such as interleukin-4, which in turn increase MMTV transcription. However, interleukin-4 is not required for in vivo virus spread, because mice lacking interleukin-4 or the STAT6 transcription factor showed wild-type infection of lymphoid and mammary tissue. In spite of this, mammary tumor incidence was decreased in STAT6 null mice.
No takes yet. Share an insight, caveat, or question.
Czarneski et al. (2001) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: