Autosomal recessive, DYT2-like primary torsion dystonia: A new family

To the Editor: Khan et al. describe three siblings with childhood onset of limb dystonia with slow progression to generalized dystonia.1 Because the children were born to unaffected parents who were first cousins, the conclusion was that the pattern of inheritance is autosomal recessive. Although this conclusion may be correct, a dominant inheritance should be considered. It is expected that in an autosomal dominant disease, one of the parents …