Key result
Oral polio vaccine administration was followed by acute flaccid paralysis in a 4-month-old male, with hypotonic monoparesis persisting for over 18 months.
Case Report (n=1)
This report describes the first officially approved case of recipient vaccine-associated paralytic poliomyelitis in Korea following OPV administration.
Documents rare VAPP after OPV in an infant; extends reports to Korea but leaves open policy implications.
This report describes a case of acute flaccid paralysis after administration of oral polio vaccine (OPV). A 4 month-old male patient with the decreased movement of left lower extremity for 1 month was transferred to the Department of Pediatrics. He received OPV with DTaP at 2 months of age. Flaccid paralysis was detected 4 weeks after OPV immunization. Attempts to isolate Sabin-like viruses in the two stool and CSF samples failed because those specimens were collected more than 2 month after the onset of paralysis. Hypotonic monoparesis (GIV/V), hypotonia and atrophy on the left lower extremity, and ipsilateral claw foot persisted for more than 18 months, while we followed him with rehabilitation therapy. This is the first case of officially approved, recipient vaccine-associated paralytic poliomyelitis in Korea.
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Kim et al. (2007) conducted a case report in Vaccine-associated Paralytic Poliomyelitis (n=1). Oral polio vaccine (OPV) was evaluated on Acute flaccid paralysis. Oral polio vaccine administration was followed by acute flaccid paralysis in a 4-month-old male, with hypotonic monoparesis persisting for over 18 months.
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