New Stilbene, Benzofuran, and Coumarin Glycosides from Morus alba

Abstract magnified image Five new compounds, including three new stilbene‐derived glycosides, one novel arylbenzofuran derivative, and one new coumarin glycoside, along with ten known compounds were isolated from the H2O extract of the bark of Morus alba L. The new compounds were assigned to the structures of 4′‐O‐β‐D‐glucopyranosyl‐2′‐hydroxyresveratrol 3‐(6‐O‐β‐D‐apiofuranosyl‐β‐D‐glucopyranoside) (1), 4′‐O‐β‐D‐glucopyranosyl‐2′‐hydroxyresveratrol 3‐(6‐O‐β‐D‐glucopyranosyl‐β‐D‐glucopyranoside) (2), 3‐O‐β‐D‐glucopyranosyl‐2′‐hydroxyresveratrol 4′‐(6‐O‐β‐D‐glucopyranosyl‐β‐D‐glucopyranoside) (3), moracin M 6‐(β‐D‐glucopyranoside) (4), and 5,7‐dihydroxycoumarin 7‐(6‐O‐β‐D‐apiofuranosyl‐β‐D‐glucopyranoside) (5) by spectroscopic means, and acid and enzymatic hydrolyses. Three compounds, 2′‐hydroxyresveratrol 2′‐(β‐D‐glucopyranoside) (7), moracin M 3′‐(β‐D‐glucopyranoside) (8), and 6,7‐dihydroxycoumarin 7‐(6‐O‐α‐rhamnopyranosyl‐β‐D‐glucopyranoside) (9), were found for the first time in Morus alba.