Key result
Serial coronary angiography revealed that 53.5% of infarct-related arteries developed complex morphological features following intracoronary urokinase and 1 month of anticoagulation.
Observational (n=43)
Serial in vivo angiographic observations reveal that infarct-related arteries have complex spatial structures, likely representing ruptured atheromatous plaques with adherent thrombus, which evolve after thrombolytic therapy.
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Post-thrombolytic complex features may reflect evolving plaque rupture; hypothesis-generating in this cohort, relevance to modern reperfusion remains open.
Nakagawa et al. (1988) conducted an observational in Acute myocardial infarction (n=43). Intracoronary urokinase followed by prolonged anticoagulation or antiplatelet therapy was evaluated on Development of type A, B, or C lesions (complex morphological features) in infarct-related coronary arteries. Serial coronary angiography revealed that 53.5% of infarct-related arteries developed complex morphological features following intracoronary urokinase and 1 month of anticoagulation.
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