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Advances in actin-myosin insights may guide mechanistic HF research; leaves open clinical translation pending prospective validation.
Recent advances in the study of muscle physiology was made possible by the application of novel experimental techniques including in vitro motility assay, molecular biology, and X-ray crystallography. A similar approach was successfully applied in studying the properties of cardiac actin-myosin interaction. Implication in clinical cardiology is also reviewed.
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Seiryo Sugiura (1999) studied this question.
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