Why the study?
Does surgical resection of cardiac nerves relieve pain in patients with angina pectoris?
Does surgical resection of cardiac nerves relieve pain in patients with angina pectoris?
This historical paper reviews early experimental and clinical efforts to treat angina pectoris pain through surgical sympathectomy, noting variable clinical success.
Variable success of cardiac nerve resection cautions against routine angina use; leaves open refined neuromodulation strategies for refractory cases.
Article1 August 1933EXPERIMENTAL AND CLINICAL STUDIES IN THE SURGICAL TREATMENT OF ANGINA PECTORISJAMES C. WHITE, M.D.JAMES C. WHITE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-7-2-229 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFollowing François-Franck's1suggestion that the pain of angina pectoris could be relieved surgically, Jonnesco,2Leriche,3Danielopolu,4and Hofer5abroad, and Coffey and Brown6in this country have developed operations for resecting part or all of the known cardiac nerves in the neck. These structures consist of the superior, middle, and inferior cervical sympathetic ganglia and their cardiac branches; also the depressor nerve when it is present as a separate branch of the vagus. All of these procedures have produced strikingly successful results in some cases, but none has been uniformly successful. As a result there has been complete confusion concerning...Bibliography1. FRANçOIS-FRANCK M: Signification physiologique de la résection du sympathique, Bull. Acad. de Méd., Paris, 1899, xli, 565. Google Scholar2. JONNESCO T: Traitement chirurgical de l'angine de poitrine par la résection du sympathique cervico-thoracique, Bull. Acad. de Méd., Paris, 1920, lxxxiv, 93. Google Scholar3. LERICHESTRICKER RR: The surgical treatment of angina pectoris, Heart, 1928, iii, 649. Google Scholar4. DANIELOPOLU D: L'angine de poitrine et l'angine abdominale, 1927, Masson, Paris. Google Scholar5. HOFER G: Zur Chirurgie des vegetativen Nervensystems bei Angina Pectoris, Wien. Med. Wchnschr., Nos. 31 and 44, 1925. Google Scholar6. COFFEYBROWN WBPK: The surgical treatment of angina pectoris, Arch. Int. Med., 1923, xxxi, 200. CrossrefGoogle Scholar7. MANDL F: Die Wirkung der paravertebralen Injektion bei Angina Pectoris, Arch. f. klin. Chir., 1925, cxxxvi, 495. Google Scholar8. SWETLOW G: Paravertebral block in cardiac pain, Am. Heart Jr., 1926, i, 1. Google Scholar9. SUTTONLUETH DCHC: Pain, Arch. Int. Med., 1930, xlv, 827. CrossrefGoogle Scholar10. WHITEATKINSGARREY JCJAWE: Experimental and clinical studies on the surgical management of angina pectoris, Arch. Surg., 1933, xxvi, 765. CrossrefGoogle Scholar11. CANNONLEWISBRITTON WBJTBW: A lasting preparation of the denervated heart for detecting internal secretion with evidence for accessory accelerator fibers from the thoracic sympathetic chain, Am. Jr. Physiol., 1927, lxxvii, 326. Google Scholar12. JONNESCOENARCHESCO DM: Nerfs cardiaques naissant de la chaine thoracique du sympathique au dessous du ganglion stellaire, Compt. rend. Soc. de biol., 1927, xcvii, 977. Google Scholar13. BRAEUCKER W: Der Brustteil des vegetativen Nervensystems und seine klinische chirurgische Bedeutung, Beit. z. Klin. d. Tuberc., 1927, lxvi, 1. Google Scholar14. KUNTZMOREHOUSE AA: Thoracic sympathetic cardiac nerves in man, Arch. Surg., 1930, xx, 609. Google Scholar15. WHITE JC: Painful aneurysms of the aortic arch, J. Am. Med. Assoc., 1932, xcix, 10. CrossrefGoogle Scholar16. WHITEWHITE JCPD: Angina pectoris, treatment with paravertebral alcohol injections, Jr. Am. Med. Assoc., 1928, xc, 1099. CrossrefGoogle Scholar17. WHITE JC: Angina pectoris, relief of pain by paravertebral alcohol block of the upper dorsal sympathetic rami, Arch. Neur. and Psych., 1929, xxii, 302. CrossrefGoogle Scholar18. WHITE JC: Angina pectoris, treatment by paravertebral alcohol injection or operation based on the newer concepts of cardiac innervation, Am. Jr. Surg., 1930, ix, 98. CrossrefGoogle Scholar19. DAVIS L: Personal communication. Google Scholar20. CONE WV: Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: JAMES C. WHITE, M.D.Affiliations: Boston, Massachusetts*Read before the American College of Physicians at Montreal, February 10, 1933. From the Cardiac Clinic and the Surgical Services of the Massachusetts General Hospital.†For want of a better word to describe the characteristic reaction to experimental coronary occlusion of this duration, the phenomena described above will be referred to hereafter as evidence of cardiac pain. But it is most important to emphasize that none of these animals was ever permitted to suffer acutely. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byConvergence of sensory processes from the heart and left ulnar nerve onto a single afferent perikaryon: A neuroanatomical study in the rat employing fluorescent tracersDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und Herzinfarkt 1 August 1933Volume 7, Issue 2Page: 229-239KeywordsAnginaGangliaHospitalsNerves ePublished: 1 December 2008 Issue Published: 1 August 1933 PDF downloadLoading ...
No takes yet. Share an insight, caveat, or question.
James C. White (1933) conducted a review in Angina pectoris. Surgical resection of cardiac nerves was evaluated.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: