Key result
Surgical treatment remains the gold standard for papillary muscle rupture following myocardial infarction, though transcatheter devices may serve as a bridge to recovery in high-risk patients.
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This review highlights that while surgery remains the gold standard for post-infarction papillary muscle rupture, emerging transcatheter and minimally invasive techniques offer new therapeutic avenues for high-risk patients.
Papillary muscle rupture (PMR) is a significant mechanical complication following myocardial infarction (MI), a condition associated with a high mortality. It results in severe mitral valve regurgitation (MR), often accompanied by cardiogenic shock and pulmonary edema, requiring both emergent medical treatment and surgical intervention. Surgical treatment includes either chordal sparing mitral valve replacement or mitral valve repair, which is associated with a high mortality. Mitral valve repair is believed to be superior to mitral valve replacement with respect to improving left ventricular function, albeit with risk of repair failure and resulting in increased cross clamp times. Concomitant coronary revascularization may improve both short- and long-term outcomes after surgery. With advances in medical innovations in the field of transcatheter devices, these devices may serve as a bridge to recovery or treatment in the setting of acute MR due to PMR. However, long-term data will be required to establish the non-inferiority of one treatment modality over the other. Management of these patients should be guided by a dedicated mitral heart team.
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Hamid et al. (2022) conducted a review in Papillary muscle rupture post-acute myocardial infarction. Mitral valve repair and replacement was evaluated. Surgical treatment remains the gold standard for papillary muscle rupture following myocardial infarction, though transcatheter devices may serve as a bridge to recovery in high-risk patients.
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