Non-alcoholic steatohepatitis and hepatic steatosis in patients with adult onset growth hormone deficiency

Adult onset growth hormone (GH) deficiency closely resembles syndrome X.1 Patients with syndrome X often suffer from obesity, dyslipidaemia, insulin resistance, and hypertension, and hepatic steatosis and non-alcoholic steatohepatitis (NASH) have also been characterised as symptoms of syndrome X.2,3 However, the relationship of GH deficiency to hepatic steatosis and NASH remains unclear. We looked for the presence of hepatic steatosis using computer tomography (CT) in a study of 18 patients with adult …