Key result
Hypertensive response to exercise, defined as systolic BP ≥210 mmHg in men and ≥190 mmHg in women or diastolic BP ≥110 mmHg, may represent a preclinical stage of essential hypertension.
Why the study?
The actual significance and definition of hypertensive response to exercise are still debated, and the underlying mechanisms are poorly understood.
Hypertensive response to exercise may represent a preclinical stage of essential hypertension related to endothelial dysfunction and vascular stiffness.
Hypothesis-generating from Level 5 data; leaves open prospective validation of exercise BP responses as hypertension predictors.
The actual significance and definition of hypertensive response to exercise (HRE) is still debated. Up to now, there is consensus in defining it as a systolic blood pressure value of either ≥ 210 mmHg in men and ≥ 190 mmHg in women or a diastolic blood pressure ≥ 110 mmHg during maximal exercise stress test. The mechanisms underlying an exaggerated blood pressure response to exercise are poorly understood; however, there are studies suggesting that HRE may represent a preclinical stadium of essential hypertension, which shares several common pathological mechanisms mostly related to an endothelial dysfunction and vascular stiffness. In this article we review the present knowledge with particular respect to prognostic significance and diagnostic and therapeutic strategies in different populations. A separate section is dedicated to athletes with HRE.
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A 2019 study conducted a review in Hypertensive response to exercise. Hypertensive response to exercise was evaluated. Hypertensive response to exercise, defined as systolic BP ≥210 mmHg in men and ≥190 mmHg in women or diastolic BP ≥110 mmHg, may represent a preclinical stage of essential hypertension.
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