Key result
Neutralizing antibodies against poliovirus types 1, 2, and 3 were detected in 96.2%, 96.8%, and 89.6% of samples, respectively, indicating a very high level of immunity in the German population.
Population
3,445 individuals in Germany, comprising a representative sample of 2,564 adults aged 18-79 years from the…
Design
Cross-sectional
Authors
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Supports high German polio immunity; leaves open longitudinal surveillance needs using new standardized cut-offs.
Cross-Sectional (n=3,445)
The German population exhibits a very high level of immunity against poliomyelitis, with newly established protective cut-off values in International Units to standardize future serological monitoring.
Diedrich et al. (2002) conducted a cross-sectional in Poliomyelitis (n=3,445). Poliovirus antibodies was evaluated on Seroprevalence of neutralizing antibodies against poliovirus type 1 (95% CI 95.5%-96.9%). Neutralizing antibodies against poliovirus types 1, 2, and 3 were detected in 96.2%, 96.8%, and 89.6% of samples, respectively, indicating a very high level of immunity in the German population.
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