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Cell production rates were studied in a group of eleven patients with carcinoma of the stomach using an in vivo technique with vincristine. In normal pyloric mucosa estimates ranged from 8 to 15 cells/1000 cells/hr, and in the carcinomas from 3 to 24 cells/1000 cells/hr. Because of the very large variation in the data, comparison between individual tumours and normal mucosa is not regarded as being worth-while at this stage. The implications of these results for previous human in vivo stathmokinetic experiments are also discussed.
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Wright et al. (1977) studied this question.
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