Key result
Coupled models technology using a unified variational approach provides insight into flow regimes across different geometrical scales in computational hemodynamics.
This review highlights recent advances in multi-scale computational hemodynamics using dimensionally-heterogeneous models to understand cardiovascular flow regimes.
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May inform computational hemodynamics research; leaves open clinical translation pending prospective validation.
The goal of this work is to gather recent advances in computational modelling aimed at tackling problems in the field of computational hemodynamics to provide insight about the flow regimes prevailing in certain vascular districts. These models are devised to retrieve the relevant physical phenomena from the different geometrical scales encountered within the cardiovascular system. Hence, we resort to the use of dimensionally-heterogeneous models, whose derivation follows a unified variational approach. Also, some issues that emerge with the use of such technology are exposed and elucidated, together with two selected examples of application. Finally, some guidelines for future research are highlighted.
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Blanco et al. (2011) conducted a review in Computational hemodynamics. Coupled models technology was evaluated. Coupled models technology using a unified variational approach provides insight into flow regimes across different geometrical scales in computational hemodynamics.
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