Key result
Women with nonischemic congestive heart failure had significantly higher heart rate variability, including SD of RR intervals (76 vs 55.3 msec; P<0.0001), compared with men.
Why the study?
Are there gender-related differences in heart rate variability among patients with congestive heart failure?
Observational (n=199)
Are there gender-related differences in heart rate variability among patients with congestive heart failure?
Absolute Event Rate: 76% vs 55.3%
p-value: p=<0.0001
Women with nonischemic congestive heart failure exhibit attenuated sympathetic activation and parasympathetic withdrawal compared to men, which may contribute to their observed survival advantage.
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May link to female survival advantage in nonischemic HF via autonomic differences; hypothesis-generating and needs prospective validation.
Aronson et al. (2000) conducted an observational in Congestive heart failure (n=199). Female gender vs. Male gender was evaluated on SD of RR intervals in patients with nonischemic heart failure (p=<0.0001). Women with nonischemic congestive heart failure had significantly higher heart rate variability, including SD of RR intervals (76 vs 55.3 msec; P<0.0001), compared with men.
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