Neutrophil-activating Protein Polymorphism of Helicobacter pylori Determines the Host Risk of Dyspepsia

This is the authors' abstract. We don't add key points for this paper.

Helicobacter pylori infection is an accepted cause of dyspepsia, according to the Rome IV criteria,1 because its eradication significantly resolves dyspepsia; however, no H pylori virulence factor that can cause dyspepsia has been identified. Here, we identified a polymorphism in H pylori neutrophil-activating protein A (NapA) closely associated with dyspepsia occurrence.