Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage.

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Growth stimulatory effect of pancreatic spasmolytic polypeptide on cultured colon and breast tumor cells1989 · 99 citations
2. 2Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium.1992 · 178 citations
3. 3Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach1995 · 176 citations
4. 4A surprising sequence homology1988 · 38 citations