Key result
18F-FDG PET/CT imaging identified multiple focal areas of increased activity in the rib, aiding in the diagnosis of primary epithelioid angiosarcoma.
Case Report (n=1)
18F-FDG PET/CT imaging may be a useful modality for diagnosing and determining the extent of primary epithelioid angiosarcoma of the bone.
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18F-FDG PET/CT may aid rare bone sarcoma diagnosis; leaves open prospective validation before practice change.
Primary epithelioid angiosarcoma (EA) of bone is rare, and the diagnosis is challenging. Herein we report a case of a 55-year-old woman with primary EA of the rib. She had progressive left posterior chest wall pain for 2 months. The chest X-ray showed a bony defect, while the chest CT scan showed bony erosions and osteolytic changes of the left 8th rib. Whole-body 18 F-FDG PET/CT imaging showed multiple focal areas of increased 18 F-FDG activity in the left posterior 8th rib, which suggested a malignant tumor with a multicentric pattern. EA was diagnosed by histopathological examination and immunohistochemistry. This is the first report of 18 F-FDG PET about a primary EA. 18 F-FDG PET/CT imaging may play a role in diagnosing this subset of angiosarcomas, as well as determining the extent of the disease.
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Huang et al. (2009) conducted a case report in Primary epithelioid angiosarcoma of the rib (n=1). 18F-FDG PET/CT imaging was evaluated on Detection of malignant tumor and extent of disease. 18F-FDG PET/CT imaging identified multiple focal areas of increased activity in the rib, aiding in the diagnosis of primary epithelioid angiosarcoma.
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