Key result
High K exposure and electroconvulsive shocks increased the output of specific amino acids in rat striatal dialysates, with effects varying by time after probe implantation.
Population
Conscious rats (striatum)
Comparison
Exposure to high K concentrations or… vs Resting release (before exposure)
Design
Preclinical
Follow-up
up to 2 weeks after implantation
Authors
Loading...
Supports timed microdialysis for rat striatal amino acid studies; extends validation of the technique for transmitter vs metabolic readouts.
Dialysis is useful to monitor extracellular transmitter amino acids in the rat striatum for a limited time after probe implantation, and for longer times to follow metabolic changes.
Jakob Korf (1985) studied this question. High K concentrations or electroconvulsive shocks vs. Resting release (before exposure) was evaluated on Extracellular levels of amino acids in dialysates of the rat striatum. High K exposure and electroconvulsive shocks increased the output of specific amino acids in rat striatal dialysates, with effects varying by time after probe implantation.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: