To the Editor:— The value of nasal spraying with chemicals has yet to be established as useful for preventing infantile paralysis in man. The conservative physician will so advise his patients and await the results of a competently conducted controlled study. The new classic experiments on monkeys that were carried out simultaneously by Armstrong and Harrison, Schultz and Gebhardt and Olitsky and Cox are well known (Armstrong, Charles, and Harrison, W. T.: Prevention of Experimental Intranasal Infection with Certain Neutrotropic Viruses by Means of Chemicals Instilled into the Nostrils,Pub. Health Rep.51:203 [Feb. 28] 1936. Sabin, A. B.; Olitsky, P. K., and Cox, H. R.: Protective Action of Certain Chemicals Against Infection of Monkeys with Nasally Instilled Poliomyelitis Virus,J. Exper. Med.63:877 [June] 1936. Schultz, E. W., and Gebhardt, L. P.: Prevention of Intranasally Inoculated Poliomyelitis in Monkeys by Previous Intranasal Irrigation with Chemical Agents,Proc.
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Paul H. Harmon (1937) studied this question.