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Choleragen, administered paren-terally, immunized adult rabbits against intestinal challenge with either living cholera vibrios or with choleragen. A degree of resistance against choleragen could be passively transferred by serum to infant rabbits. These results suggest that choleragen offers promise as an effective immunogen against cholera although additional study is needed before any field studies can be performed.
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Finkelstein et al. (1967) studied this question.
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