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Summary 1. Phosphoglucomutase phenotypes have been studied in several generations of the family of an individual heterozygous at each of the three loci, PGM1, PGM2, and PGM3. 2. PGM1 and PGM2 phenotypes were determined using red cells. Fibroblasts grown in tissue culture were used for PGM3 phenotyping. 3. The family results support the genetical hypothesis based on the analysis of dizygotic twin pairs that the PGM3 isozyme patterns found in the placenta are determined by two alleles, PGM13 and PGM23. 4. Locus PGM3 is not closely linked to locus PGM2 5. The data also support the previous findings that locus PGM1 is not closely linked to PGM2 or PGM3.
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Parrington et al. (1968) studied this question.
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