Key result
High-frequency ultrasound imaging of whole blood coagulation in samples from 12 healthy subjects revealed that changes in structural parameters significantly correlated with velocity and attenuation.
Population
In vitro whole blood samples from 12 healthy subjects
Design
Preclinical
Authors
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Provides a novel in vitro tool for coagulation research; leaves open translation to clinical or in vivo settings.
High-frequency ultrasound time-correlation imaging provides a novel method to visualize and quantify in vitro blood coagulation dynamics, revising previous mechanical models.
Plag et al. (2012) studied Blood coagulation (n=12). High-frequency ultrasound imaging (20 MHz) was evaluated on Changes in structural parameters, velocity, and attenuation during whole blood coagulation. High-frequency ultrasound imaging of whole blood coagulation in samples from 12 healthy subjects revealed that changes in structural parameters significantly correlated with velocity and attenuation.
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