Incidence of Acute Hypertension with Sevoflurane and Propofol during Laryngoscopy and Endotracheal Intubation In Normotensive Patients

OBJECTIVES: The present study was designed to assess the comparison of frequency of acute hypertension with sevoflurane and propofol during laryngoscopy and endotracheal intubation in normotensive patients in general operation theater (OT). METHODOLOGY: This was a four months duration cross-sectional study during which a total of 110 patients of both the genders were recruited. The patients were divided into two groups i.e. group A receiving propofol consisted of 30 male and 25 female patients and group B receiving sevoflurane also consisted of 30 male and 25 female patients. Blood pressure (BP) was recorded four times as pre-induction values, T1 (1 minute after laryngoscopy), T2 (3 minutes after laryngoscopy) and T3 (5 minutes after laryngoscopy). RESULTS: Pre-induction systolic blood pressure (SBP) was normal in both the groups. The SBP in both the groups A and B were acutely increased in T1 while it decreased in T2 and became normal in T3 in both the groups. Pre-induction diastolic blood pressure (DBP) was normal in both the groups. The DBP was acutely increased in T1, decreased in T2 and became normal in T3 in both the groups. CONCLUSION: These results show that both the drugs sevoflurane and propofol can cause severe hypertension soon after laryngoscopy and caution should be taken during laryngoscopy/ endotracheal intubation.