Key result
Coxsackievirus A6-associated hand, foot, and mouth disease presented with atypical features, including widely spread rashes, crust formation in 100% of cases, and onychomadesis in 37.5% of followed patients.
Observational (n=28)
CA6-associated HFMD presents atypically with widely spread rashes, early crust formation, and a high rate of subsequent onychomadesis, requiring careful differential diagnosis.
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May warrant CA6 consideration in atypical HFMD differentials; case reports leave open population prevalence and outcomes.
Kobayashi et al. (2013) conducted an observational in Coxsackievirus A6-associated hand, foot, and mouth disease (n=28). Coxsackievirus A6 infection was evaluated on Clinical manifestations including crust formation and onychomadesis. Coxsackievirus A6-associated hand, foot, and mouth disease presented with atypical features, including widely spread rashes, crust formation in 100% of cases, and onychomadesis in 37.5% of followed patients.
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