Hyperinsulinism and Cushing's Syndrome

Many reports of the association of malignant neoplasms and Cushing's syndrome have appeared in the past few years, and a syndrome of ectopic adrenocorticotrophin production has been clearly defined (Bagshawe, 1960; Liddle et al., 1963). The purpose of this paper is to describe its occurrence with malignant insulinoma and to draw attention to certain similarities between ectopic adrenocorticotrophin production and pluriglandular syndrome.