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Development of antibiotics to treat infections caused by multidrug‐resistant gram‐negative bacilli has lagged significantly behind development of antibiotics to treat infections with gram‐positive pathogens. Although a few promising drugs have entered early clinical development, more must be done to preserve the utility of currently available antibiotics and to ensure a pipeline of efficacious, safe antibacterials.
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George H. Talbot (2010) studied this question.
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