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A dual responsive surface is constructed on hydrophilic polymer brushes to modulate cell migration ability on demand. The responsibility is based on the dynamic host–guest interaction between β-CD and azobenzene. Both competitive guest molecules and UV radiation are able to release azobenzene-REDV from the substrate, weakening the cell–substrate interaction and modulating the cell migration rate.
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Ren et al. (2016) studied this question.
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