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Sifting through the surface: Permselective core/shell microgels have been prepared by using a labile cross-linker, which can be cleaved stoichiometrically to control the porosity of the shell. Proteins that are smaller than the pore size are allowed to permeate through the shell to bind with the core-bound ligand (arrows; see picture).
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Nayak et al. (2004) studied this question.
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