Key result
Glycemic indices (HbA1c and fasting glucose) significantly predicted mean platelet volume and platelet distribution width in diabetic patients, but not in diabetic MDS patients.
Population
90 individuals, including 30 with primary myelodysplastic syndromes with normal platelet count and…
Design
Cross-sectional
Authors
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May inform macrovascular risk stratification via platelet indices in diabetes; leaves open utility in diabetic MDS.
Cross-Sectional (n=90)
Platelet morphology markers correlate with glycemic indices in diabetic patients but not in diabetic MDS patients, suggesting altered platelet morphology may serve as a marker for macrovascular disease risk or early myelodysplasia.
Dalamaga et al. (2010) conducted a cross-sectional in Diabetes mellitus and myelodysplastic syndromes (n=90). Glycemic indices (HbA1c and fasting glucose) vs. Non-diabetic, non-MDS controls was evaluated on Associations between platelet morphology markers (MPV, PDW) and glycemic indices. Glycemic indices (HbA1c and fasting glucose) significantly predicted mean platelet volume and platelet distribution width in diabetic patients, but not in diabetic MDS patients.
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