Why the study?
Is mean platelet volume increased in patients with diabetes mellitus compared to non-diabetic controls?
Population
Patients with diabetes mellitus
Design
Case-control
Authors
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May signal heightened thrombotic risk in diabetes; hypothesis-generating for MPV as biomarker, pending prospective validation.
Is mean platelet volume increased in patients with diabetes mellitus compared to non-diabetic controls?
Mean platelet volume is significantly elevated in patients with diabetes mellitus, suggesting a potential mechanism for increased platelet reactivity and vascular complications.
Sharpe et al. (1993) studied this question.
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