Key result
Type 2 diabetes linked to ~0.5 fL higher mean platelet volume versus non-diabetic controls.
Why the study?
A comprehensive analysis of the relationship between mean platelet volume and glycemic status in diabetes mellitus is lacking.
Does Mean Platelet Volume differ between diabetics and non-diabetics, and does it correlate with glycemic control and vascular complications?
Population
100 patients admitted in medicine wards
Comparison
50 diabetic patients vs 50 non-diabetic controls
Authors
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May support MPV monitoring in poor glycemic control; leaves open prospective validation before clinical use.
Cross-Sectional (n=100)
No
Does Mean Platelet Volume differ between diabetics and non-diabetics, and does it correlate with glycemic control and vascular complications?
Absolute Event Rate: 9.012% vs 8.52%
p-value: p=0.027
Mean platelet volume is elevated in diabetic patients and correlates with glycemic control, serving as a potential simple marker for platelet hyperactivity and vascular complications.
E. Sumanraj (2019) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=100). Type 2 Diabetes Mellitus vs. Non-diabetics was evaluated on Mean Platelet Volume (MPV) (p=0.027). Type 2 diabetes was associated with a significantly higher mean platelet volume compared to non-diabetic controls (9.012 fL vs 8.52 fL, p=0.027).
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